Combination of Serratus Anterior and Pectoral Nerve Blocks (PECS II) as Main Anesthetic Method in Breast Cancer Surgery

  • End date
    Jul 20, 2023
  • participants needed
  • sponsor
    Samsun University
Updated on 4 October 2022


Aim of this study is to determine the success of combined serratus anterior and PECS-2 block as the main anesthetic method in breast cancer surgery and also to investigate the patient acceptability of this combination and its relationship with surgeon satisfaction.


Breast conserving surgery or mastectomy is applied in the surgical treatment of breast cancer. Axillary interventions range from sentinal lymph node biopsy to lymph node dissection. Clinically significant acute pain develops following breast surgery in 35% of patients.

Today, regional anesthesia is widely used as an opioid-sparing strategy in the treatment of acute postoperative pain. New fascial plane blocks have been developed as alternative or complementary techniques for chest wall analgesia, including pectoral nerve blocks (PECS1-2) and serratus plane block.

In order to reduce the risk of perioperative morbidity and mortality and to meet the patient demand, the demand for awake surgery is increasing in institutions.

Therefore, a prospective observational case series was conducted to explain the efficacy, patient acceptability, and surgeon satisfaction of combined serratus anterior and PECS-2 block as the main anesthetic method for breast cancer surgery.

Condition Anesthesia
Treatment serratus anterior block and PECs II block combination
Clinical Study IdentifierNCT05427292
SponsorSamsun University
Last Modified on4 October 2022


Yes No Not Sure

Inclusion Criteria

Patients between the ages of 18-80 and ASA I-III who will undergo unilateral breast cancer surgery will be included in the study

Exclusion Criteria

Patients with previous breast surgery other than excisional biopsy
bleeding disease
local infection at the injection site
history of local anesthetic allergy
psychiatric disease (depression, mania, schizophrenia or antipsychotic drug use)
history of opioid use for more than 4 weeks
Patients with body mass index (BMI) >40kg/m2 and
chest deformity (pectus excavatum and pectus carinatum) will be excluded from the study
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