The Effect of Exposure to Aversive Non-verbal Vocalizations on Pain Tolerance (CRYPAIN)

  • participants needed
  • sponsor
    Centre Hospitalier Universitaire de Saint Etienne
Updated on 9 December 2022
Accepts healthy volunteers


Humans produce non-verbal vocalizations (shouting, growling, screaming), laughter, ...) in various contexts that are likely to perform biological functions.

and important social issues. Yet despite their importance in the human vocal repertoire, the mechanisms and functions of non-verbal vocalizations remain little studied and poorly understood including in humans.

In this context, the investigators wish to examine how the perception of vocalizations non-verbal aversive behaviours influence pain tolerance in healthy adults.


Humans produce nonverbal vocalisations such as screams, grunts, roars, cries and laughter across a variety of contexts. Yet despite the prominence and apparent importance of these nonverbal sounds in human communication, the investigators still know very little about their influence on human perception and behaviour. That's why, in this study, the investigators will examine specifically the influence of nonverbal vocal perception on pain tolerance.

The remainder of the study will involve up to three trials of a pain tolerance (cold pressor) task, during which the investigators will ask participants to listen to vocalisations (e.g., babies' cries or babbling) while submerging the participant's hand in bath of circulating cold water.

The results of the study will contribute to theoretical understanding of the functions of nonverbal vocal communication in humans, in particular the influence of nonverbal vocal and perception (of babies' cries) on pain tolerance.

Condition Healthy
Treatment Cold pressor task (CPT), index NOL, Playback Experiments, Video-pupillometry
Clinical Study IdentifierNCT04423874
SponsorCentre Hospitalier Universitaire de Saint Etienne
Last Modified on9 December 2022

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