Does Positive Pressure Extubation Reduce Postoperative Desaturation? (EXTUBPOS)

  • End date
    Jul 20, 2024
  • participants needed
  • sponsor
    University Hospital, Lille
Updated on 4 October 2022


Single-center, prospective, controlled, parallel, randomized, single-blind study comparing the conventional extubation technique to two positive pressure extubation techniques on postoperative desaturations


Study realise on university hospital on Lille in France. Patients inclusion is prospective and randomised in three groups. First group : extubation is realised with aspiration in tracheal tube during removal tube Second group : extubation is realised without aspiration but with APL valve set to 20cmH20 Third group : extubation is realised without aspiration but with ventilator parameters were set for PSV mode (inspiratory pressure of 10cmH2O and PEEP identical to that administered in the operating room

Condition Extubation, Postoperative Complications, Lung Ultrasound Score
Treatment positive pressure during extubation procedure
Clinical Study IdentifierNCT05295095
SponsorUniversity Hospital, Lille
Last Modified on4 October 2022


Yes No Not Sure

Inclusion Criteria

Visceral or urological surgery
Scheduled surgery
Surgical or patient requirement: placement of an arterial catheter
Supine position
Post-surgical extubation scheduled in the operating room
Minimum age of 18 years
Informed and signed consent

Exclusion Criteria

Severe obesity (BMI over 35kg/m2)
pregnant woman
Acute or chronic preoperative respiratory pathology
Sleep apnea syndrome
Inability to receive informed information (does not speak, read or understand French)
Patient under guardianship or curatorship
Lack of social security coverage
History of intubation or criteria for difficult intubation or ventilation
Clear my responses

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