Evaluation of Hearing Aids Rehabilitation Within Age-related Hearing Loss Population. (AGEHEAR)

  • End date
    Apr 28, 2024
  • participants needed
  • sponsor
    University Hospital, Toulouse
Updated on 4 October 2022
hard of hearing
Accepts healthy volunteers


Hearing aids restore efficiently some auditory functions in age-related hearing loss (ARHL or presbycusis) providing to the elderly an access to oral communication and a return to social life. However, a most of the assessments of their efficacy focus on speech recognition. Spatial hearing and localization are anothers important auditory functions merely evaluated.

The purpose of this study is to evaluate the hearing aids benefits for spatial hearing.


The main objective is to evaluate the hearing aids benefits for spatial hearing with a multidisciplinary approach combing psychophysics, and Positron Emission Tomography (PET) brain imaging in a before/after experimental design. The novelty of the proposal is both theoretical and methodological: the team aim is to identify neural correlates of spatial hearing after hearing rehabilitation and evaluate the evolution of spatial hearing abilities once subjects with presbycusis are fitted with hearing aids. The assessment of spatial hearing processing will rely on both a virtual visuo-auditory 3D immersive platform and functional neuroimaging using PET scan. This project will provide crucial elements for understanding and improving the rehabilitation of age-related hearing loss.

Condition Hearing Loss
Treatment quality of life assessment, PET examination
Clinical Study IdentifierNCT05331404
SponsorUniversity Hospital, Toulouse
Last Modified on4 October 2022


Yes No Not Sure

Inclusion Criteria

For presbyacusics subjects
Subjects aged over 50 with a difference in symmetrical audiometric thresholds (< 15 dB) between the two ears and requiring hearing aids
Affiliation to a social security scheme or equivalent
Acceptance of the protocol and signature of the consent form
For older people with normal hearing
Subjects matched in age (+/- 2 years) and gender with the presbycusis group
Affiliation to a social security scheme or equivalent
Acceptance of the protocol and signature of the consent form
Subjects with normal hearing, with hearing thresholds of 20 dB < 2kHz and 40 dB < 4kHz
For young people with normal hearing
Subjects aged between 18 and 40 years old
Symmetric normal hearing
Affiliation to a social security scheme or equivalent
Normally hearing subjects with audiometric thresholds < 20 dB
Acceptance of the protocol and signature of the consent form

Exclusion Criteria

Persons under a legal protection regime for adults (safeguard of justice, guardianship, curator ship, institutionalized, or under mandate for future protection)
History of associated neurological pathology
Contraindications to PET
Cognitive impairment confirmed by the Montreal Cognitive Assessment (MOCA) test (for presbyacusic subjects and normal-hearing elderly subjects)
Taking psychotropic drugs
History of epilepsy
Pregnant or breastfeeding woman
Participation in another intervention protocol
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