Sensitivity of Multiparametric MRI in Differentiation Between Muscle Invasive and Non-muscle Invasive Urinary Bladder Cancer

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    Helwan University
Updated on 11 July 2022
invasive bladder cancer
bladder tumor


Differentiation between non-muscle-invasive bladder cancer (NMIBC) and muscle-invasive bladder cancer (MIBC) is a cornerstone in the treatment plans.Therefore, this study will try to evaluate the sensitivity and reliability of mpMRI in accurate diagnosis of cancer bladder.

Primary objective: to detect the sensitivity of multiparametric MRI in differentiation between muscle Invasive and non-muscle invasive Urinary Bladder Cancer in relation to the conventional cystoscopy and histopathological examination of the biopsy.

Condition Cancer, Bladder
Treatment multiparametric MRI on the bladder, diagnostic cystoscopy +/- TURBT
Clinical Study IdentifierNCT05324033
SponsorHelwan University
Last Modified on11 July 2022


Yes No Not Sure

Inclusion Criteria

All patients diagnosed with NMIBC or MIBC during diagnostic cystoscopy or by any radiologic investigation in the Urology department of Helwan university hospitals without being restricted to age or sex
All histological types of bladder cancer
Newly diagnosed, recurrent cases, or even patients undergoing follow-up cystoscopy

Exclusion Criteria

Patients with elevated renal function according to their age as this will be a contraindication to DCE MRI
Patients with absolute contraindication to MRI (e.g.: metallic prosthesis)
Patients with contraindication to undergo TURBT (e.g.: unfit for surgery)
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