Serum and Wound Vancomycin Levels Following Intrawound Administration in Primary Total Hip Arthroplasty

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  • participants needed
  • sponsor
    The Affiliated Hospital of Qingdao University
Updated on 18 October 2022


The purpose of this study is to determine the intra-articular and serum levels of vancomycin over the first 24 hours postoperatively after intra-articular administration of a standard dose of vancomycin in primary total hip arthroplasty.

Condition Hip
Treatment Intrawound administration of vancomycin after closure of the arthrotomy
Clinical Study IdentifierNCT05338008
SponsorThe Affiliated Hospital of Qingdao University
Last Modified on18 October 2022


Yes No Not Sure

Inclusion Criteria

Age over 18
Total hip arthroplasty for advanced hip diseases including femoral neck fracture, developmental dysplasia of hip, and osteonecrosis of the femoral head

Exclusion Criteria

Diminished mental capacity
Vancomycin allergy
Chronic kidney disease stage III and stage IV
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