No Drainage During Transoral Endoscopic Thyroidectomy Vestibular Approach(TOETVA)

  • End date
    Oct 1, 2023
  • participants needed
  • sponsor
    Second Affiliated Hospital, School of Medicine, Zhejiang University
Updated on 13 July 2022


This study evaluates the viability and safety of no drainage tube placement during transoral endoscopic thyroidectomy vestibular approach in treatment of patients with papillary thyroid carcinoma.


Transoral endoscopic thyroidectomy vestibular approach (TOETVA) is widely used due to its excellent cosmetic effect without scars on the body surface. In prevention of postoperative hemorrhage, a postoperative drainage tube is routinely placed in the surgical area. However, current opinion suggest that under the circumstance of strict and effective intraoperative hemostasis, routine application of drainage tube is unnecessary in conventional open thyroidectomy(COT). The research about drainage placement decision during endoscopic thyroidectomy is scarce currently. This study evaluates the viability and safety of no drainage tube placement during TOETVA on papillary thyroid carcinoma.

Patients allocated to the intervention group will implace no drainage tube during TOETVA and those allocated in control group will implace one drainage tube routinely.

The incidence of postoperative complications will be evaluated. The time of postoperative hospital-stay and operation time will be evaluated as well. At the same time, blood test results like WBC and CRP will be evaluated 1 day after surgery.

Condition Drainage, Thyroid Cancer
Treatment no drainage tube applied
Clinical Study IdentifierNCT04931576
SponsorSecond Affiliated Hospital, School of Medicine, Zhejiang University
Last Modified on13 July 2022


Yes No Not Sure

Inclusion Criteria

Patients undergoing thyroid surgery for the first time
The surgical method is TOETVA
There is no lateral cervical lymph node metastasis assessed before surgery
Fine-needle aspiration revealed palpilary thyroid carcinoma
It meets the surgical indications and has no obvious surgical contraindications

Exclusion Criteria

previous history of thyroid surgery
conventional open thyroidectomy, endoscopic thyroidectomy areola approach or axillary approach
patients undergoing cervical lateral lymph node dissection
past or current history of hyperthyroidism
history of combined hypertension, diabetes, coagulation dysfunction, or other important organ dysfunction diseases
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