Vitamin B12 and Dextrose for Median Nerve Hydrodissection

  • End date
    Dec 11, 2024
  • participants needed
  • sponsor
    National Cheng-Kung University Hospital
Updated on 11 July 2022
vitamin b12
entrapment neuropathies
electrophysiological studies


Carpal tunnel syndrome is the most common peripheral entrapment neuropathy of the upper limb. Previous experiments found that ultrasound-guided median nerve hydrodissection with 5% dextrose water could ameliorate the condition of carpal tunnel syndrome. Oral administration of vitamin B 12 had been reported to reduce the discomfort from peripheral neuropathy although the level of evidence is not strong. This prospective, double-blind randomized control trial aims to compare the effects of different kinds of the injection agents on carpal tunnel syndrome.

Condition Carpal Tunnel Syndrome
Treatment Ultrasound-guided nerve hydrodissection
Clinical Study IdentifierNCT05423028
SponsorNational Cheng-Kung University Hospital
Last Modified on11 July 2022


Yes No Not Sure

Inclusion Criteria

Age between 20-80 year-old
Diagnosis (carpal tunnel syndrome) was confirmed using an electrophysiological study

Exclusion Criteria

Previously undergone wrist surgery or steroid injection for CTS
Inflammation status
Brachial plexopathy
Cervical radiculopathy
Autoimmune disease
Thoracic outlet syndrome
Clear my responses

How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact



Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

Learn more

Similar trials to consider


Browse trials for

Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer

user name

Added by • 



Reply by • Private

Lorem ipsum dolor sit amet consectetur, adipisicing elit. Ipsa vel nobis alias. Quae eveniet velit voluptate quo doloribus maxime et dicta in sequi, corporis quod. Ea, dolor eius? Dolore, vel!

  The passcode will expire in None.

No annotations made yet

Add a private note
  • abc Select a piece of text from the left.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.
Add a private note