Efficacy of PRF Application on Clinical Parameters and GCF Platelet-derived Growth Factor-BB and Periostin Levels
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- STATUS
- Recruiting
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- days left to enroll
- 52
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- participants needed
- 14
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- sponsor
- University of Baghdad
Summary
Determine the efficacy of the non-invasive application of PRF on periodontal clinical parameters(pocket reduction) and the levels of PDGF-BB and Periostin in the gingival crevicular fluid.
Description
The adjunctive use of PRF with conventional ScRp may improve clinical healing, decrease tissue morbidities such as pain and discomfort, increase patient acceptance, reduce treatment time. Since PRF can be utilized as a safe, natural method to repair tissues at a low cost. Our aim is to evaluate the effectiveness of the non-invasive application of PRF as an adjunct to ScRp in patients with stage III grade B periodontitis through measurements of gingival crevicular fluid levels of PDGF-BB and Periostin before and after treatment and compare it with ScRp alone. A split-mouth procedure will be performed to reduce confounders as possible.
Details
| Condition | Periodontitis |
|---|---|
| Treatment | Platelet rich fibrin |
| Clinical Study Identifier | NCT05178771 |
| Sponsor | University of Baghdad |
| Last Modified on | 21 July 2022 |
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