Antibiotic Prophylaxis for TEVAR

  • End date
    Jan 1, 2023
  • participants needed
  • sponsor
    First Affiliated Hospital of Zhejiang University
Updated on 19 June 2022


The infection rate of thoracic endovascular aortic repair (TEVAR) is unknown due to a lack of epidemiological data. The rate currently available comes from researches conducted decades ago, when open surgery was the standard of care. Because of the potentially fatal consequences of a stent graft infection in the thoracic aorta, we tend to prescribe antibiotic prophylaxis for at least three days. In this study, we are going to collect data on patients receiving TEVAR in the past five years and provide the following information: a. the infection rate (MAGIC classification), b. the rate of fever, c. the results of the lab tests, such as the WBC count and C-reaction protein. d. risk factors associated with infection and fever.

Condition Aortic Dissection, Aortic Diseases, Aortic Aneurysm, Thoracic, Coarctation of Aorta, Hematoma; Aorta
Treatment thoracic endovascular aortic repair
Clinical Study IdentifierNCT05405790
SponsorFirst Affiliated Hospital of Zhejiang University
Last Modified on19 June 2022


Yes No Not Sure

Inclusion Criteria

Diagnosed with thoracic aortic diseases
Received TEVAR

Exclusion Criteria

Suspected infectious aortic disease, such as a mycotic aneurysm
TEVAR combined with open surgery
Antibiotics have been used more than 24 hours before the operation
Combined with immune deficiency disease or using hormone or immunosuppressant;
The treatment is for the complications of TEVAR, such as endoleak
Endovascular aortic repair for abdominal aortic disease
History of open aortic surgery or heart surgery
Revascularization of visceral arteries during the TEVAR
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