Pilot Study of Add-On Fycompa (Perampanel)Treatment for Catamenial Epilepsy

  • participants needed
  • sponsor
    University of Florida
Updated on 5 February 2023


The purpose of the proposed investigation is to carry out a pilot study of add-on perampanel (Fycompa) in women with perimenstural (C1) catamenial epilepsy. Perampanel, a noncompetitive AMPA receptor antagonist, is uniquely positioned to decrease progesterone receptor mediated excitotoxicity. This mechanism of action would allow a novel use of perampanel as an effective treatment of C1 catamenial epilepsy.

Condition Catamenial Epilepsy
Treatment Fycompa, Fycompa with a boost
Clinical Study IdentifierNCT05201703
SponsorUniversity of Florida
Last Modified on5 February 2023

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