Intravascular Ultrasound Guided PCI in STEMI (iSTEMI)

  • End date
    Feb 1, 2031
  • participants needed
  • sponsor
    Thomas Engstrom
Updated on 18 June 2022
chest pain
percutaneous coronary intervention
left bundle branch block


The purpose of is study is to investigate whether intravascular ultrasound-guided (IVUS) percutaneous coronary intervention (PCI) improve the clinical outcome of patients with ST-segment elevation myocardial infarction treated with primary PCI.

Condition ST Elevation Myocardial Infarction
Treatment PCI + Ischemic conditioning, Stent with ultrasound
Clinical Study IdentifierNCT04775914
SponsorThomas Engstrom
Last Modified on18 June 2022


Yes No Not Sure

Inclusion Criteria

Age ≥18 years
Acute onset of chest pain with <12 hours duration
STEMI as characterized by 2 mm ST elevation in 2 or more V1 through V4 leads or presumed new left bundle branch block with minimum of 1 mm concordant ST elevation or 1 mV ST-segment elevation in the limb lead (II, III and aVF, I, aVL) and V4-V6 or ST depression in 2 or more V1 through V4 leads indicating posterior AMI

Exclusion Criteria

Pre-PCI TIMI flow 0 or 1 Potential pregnancy Inability to provide informed consent
Unwillingness to consent Unavoidable to use thrombectomy Spontaneous coronary artery
dissection Time from symptoms onset to PPCI > 12 hours Culprit in bypass graft Other reason
for not including the patient
Exclusion Criteria (iSTEMI)
Potential pregnancy Inability to understand information in order to provide informed
consent Unwillingness to consent Spontaneous coronary artery dissection Time from symptoms
inset to PPCI > 12 hours Culprit in bypass graft Other reason
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