Exploring the Recovery Function of Sleep in Neurodegeneration (RFSN)
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- STATUS
- Recruiting
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- End date
- Jun 17, 2026
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- participants needed
- 200
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- sponsor
- University of Zurich
Summary
The overall objective of this study is to identify the best approach for assessing the recovery function of sleep in neurodegenerative diseases associated with abnormal protein aggregation with regard to the conception of future intervention studies. To this end, the investigators will follow an exploratory approach in a preferably broad data set collected in patients with neurodegenerative diseases associated with abnormal protein aggregation and in healthy humans.
Description
First, the investigators want to assess the relationship between sleep parameters (e.g. sleep intensity) and behavioral/cognitive performance and subjective measures (e.g. sleep quality, mood, and sleepiness) in patients with neurodegenerative disorders associated with abnormal protein aggregation. Healthy subjects will be assessed for procedure validation and reference purposes. Second, the investigators want to probe whether associations can be influenced by modulation of sleep parameters by means of auditory stimulation.
Details
| Condition | Neurodegenerative Diseases |
|---|---|
| Treatment | Auditory stimulation |
| Clinical Study Identifier | NCT05402488 |
| Sponsor | University of Zurich |
| Last Modified on | 17 June 2022 |
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