Subclinical Hypothyrodism and Ovarian Reserve

  • End date
    Aug 1, 2023
  • participants needed
  • sponsor
    Assiut University
Updated on 16 June 2022


This study aimed to evaluate the potential association of subclinical hypothyrodism and ovarian reserve in reproductive age in age groups more than 35 and age groups less than 35 using retrospective study included women with subclinical hypothyrodism and controls .Evaluation of potential association of antithyroid antibodies positivity on ovarian reserve

Primary outcome:

Measure the association of SCH with ovarian reserve markers (basal FSH ,LH/basal AFC /AMH)


Thyroid dysfunction is one of the commonest disorders in women of reproductive age .there is association between subclinical hypothyrodism and infertility and ovarian reserve .It's known that subclinical hypothyrodism can be associated with reduced ovarian reserve in women more than 35 years old .Aclear association between subclinical hypothyrodism and ovarian reserve not established in reproductive age in women less than 35 .This retrospective study investigate serum thyroid hormone /Antithyroid hormone ,ovarian reserve markers (basal FSH,AMH,Antral follicle count on day 2-4/prolactin level .

Condition Fertility Disorders
Treatment retrospective charts reviewing
Clinical Study IdentifierNCT05409729
SponsorAssiut University
Last Modified on16 June 2022


Yes No Not Sure

Inclusion Criteria

All reproductive age groups included women less than 35 and women more than 35

Exclusion Criteria

Previous ovarian surgery Women with long term thyroid hormone replacement Endometriosis History of radiotheraby
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