3DPCT Combined With CT Guided RISI in the Treatment of Thoracic Malignant Tumors
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- STATUS
- Recruiting
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- End date
- Apr 30, 2026
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- participants needed
- 30
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- sponsor
- Peking University Third Hospital
Summary
The main technical difficulties in radioactive iodine-125 seed implantation (RISI) lie in the complexity of operation and the control of operation quality. The current data shows that under the combined guidance of 3D-printing template and CT, the accuracy of RISI has been significantly improved, and the actual target dose could meet the design requirements of preoperative plan.
At present, 3D printing templates (3DPT) are divided into non-coplanar templates (3DPNCT) and coplanar templates (3DPCT). In clinical practice, due to the complex technical requirements, high production cost and long printing time of 3DPNCT, a considerable number of patients can also complete the treatment with 3DPCT. Moreover, compared with 3DPNCT, 3DPCT has the advantages of accurate needle path control, fast needle path adjustment, convenient for intraoperative real-time optimization, without waiting for printing time, easy for doctors to master, lower cost than 3DPNCT, and easy to carry out at the grass-roots level. Therefore, this study intends to explore 3DPCT technology to further clarify: (1) the accuracy of 3DPCT assisted CT guided RISI in the treatment of thoracic malignant tumors; (2) the short-term efficacy and toxicity of 3DPCT assisted CT guided RISI in the treatment of thoracic malignant tumors.
Details
| Condition | Radioactive Iodine-125 Brachytherapy, Thoracic Cancer, 3D Printing Coplanar Template, Nuclear Radiation Effects |
|---|---|
| Treatment | Radioactive seed brachytherapy |
| Clinical Study Identifier | NCT05351268 |
| Sponsor | Peking University Third Hospital |
| Last Modified on | 16 June 2022 |
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