Improving Blood Lipid Management in Symptomatic Intracranial Atherosclerotic Stenosis on Clinical Outcome (sICASBLM)
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- STATUS
- Recruiting
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- End date
- May 1, 2024
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- participants needed
- 180
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- sponsor
- Nanjing First Hospital, Nanjing Medical University
Summary
sICASBLM is a prospective controlled trial, to asses the impact of improving blood lipid management on clinical outcome of moderate to severe symptomatic intracranial atherosclerotic stenosis patients (LDL-C>1.8mmol/L) without endovascular therapy.
Description
sICASBLM aims to determine the effectiveness of conventional lipid management combined with PCSK9 inhibitors compared to conventional lipid management (atorvastatin 20-40mg or rosuvastatin 10-20mg or simvastatin 20-40mg) in reducing the incidence of recurrent stroke in patients with moderate to severe symptomatic intracranial atherosclerotic stenosis (LDL-C>1.8mmol/L) without endovascular therapy.
Details
| Condition | Intracranial Artery Stenosis |
|---|---|
| Treatment | PCSK9 Inhibitor |
| Clinical Study Identifier | NCT05397405 |
| Sponsor | Nanjing First Hospital, Nanjing Medical University |
| Last Modified on | 15 June 2022 |
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