The Effect of Solifenacin Used for Lower Urinary Tract Symptoms on Sexual Function

  • End date
    Jun 3, 2024
  • participants needed
  • sponsor
    Istanbul University
Updated on 4 June 2022


This study aims to determine whether Solifenacine used for lower urinary tract symptoms improves sexual function and if so does this improvement differs between premenopausal and postmenopausal women.


Solifenacin is an anticholinergic drug that is commonly used for lower urinary tract symptoms such as urgency, frequency and urge urinary incontinence. Solifenacin use and sexual function improvement is presented in some research, but the correlation between the improvement in sexual function and LUTS symptoms is yet not investigated. Also the effect on sexual function in premenopausal vs postmenopausal women are unknown.

Condition Urge Incontinence, Urgency-frequency Syndrome
Treatment No intervention
Clinical Study IdentifierNCT05391425
SponsorIstanbul University
Last Modified on4 June 2022


Yes No Not Sure

Inclusion Criteria

Women presented in Arnavutkoy State Hospital Gynecology Clinic with lower urinary tract symptoms that are planned to start treatment with Solifenacin 5 mg (Vesicare 5mg)
Patients agreed to involve in the study, having discussed other treatment options and possible side effects of the medication
Informed consent obtained

Exclusion Criteria

urinary tract infection
stress urinary incontinence
urinary retention
grade 2 or above pelvic organ prolapse according to POP-Q scale
Solifenacin contraindications such as narrow angle glaucoma, allergy of Solifenacin or other components of the drug
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