Role of the Immune Environment in Response to Therapy in Breast Cancer

  • End date
    Dec 31, 2032
  • participants needed
  • sponsor
    Abramson Cancer Center of the University of Pennsylvania
Updated on 15 June 2022


This is an observational case-control study of tissues collected from women with ER+HER2- breast cancers. The immune environments of these cancers will be compared to triple negative and HER2+ breast cancers. No randomization or changes to standard of care treatment will occur as part of the study.

Condition Breast Cancer, ER Positive Breast Cancer, HER2-negative Breast Cancer, TNBC - Triple-Negative Breast Cancer
Treatment Collection of personal health information from women treated at the University of Pennsylvania under an approved HIPAA waiver.
Clinical Study IdentifierNCT05396612
SponsorAbramson Cancer Center of the University of Pennsylvania
Last Modified on15 June 2022


Yes No Not Sure

Inclusion Criteria

Women 18 years of age or older with non-metastatic breast cancer undergoing surgical
resection in the University of Pennsylvania Health System

Exclusion Criteria

Males Children Pregnant individuals
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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