De-implementation of Outdated Colonoscopy Surveillance Interval Recommendations Among Patients With Low-risk Adenomas (DESIRE)

  • days left to enroll
  • participants needed
  • sponsor
    Kaiser Permanente
Updated on 3 June 2022
Accepts healthy volunteers


The purpose of this study is to compare the effectiveness of three standard of care outreach approaches (i.e., mailed letter, secure message, and telephone call) on patient adoption of the new 10-year colonoscopy surveillance interval recommendation for a random sample of health plan members who have a now-outdated 5-year surveillance interval due to a finding of 1-2 small adenomas at their prior colonoscopy. The primary study endpoint is the proportion of patients in each outreach arm who adopt the new 10-year colonoscopy surveillance interval.

Condition Polyp of Colon
Treatment Outreach
Clinical Study IdentifierNCT05389397
SponsorKaiser Permanente
Last Modified on3 June 2022


Yes No Not Sure

Inclusion Criteria

Kaiser Permanente Northern California (KPNC) membership>12 months
Primary medical center is either KP San Rafael, KP San Francisco, KP San Leandro, or KP Walnut Creek
-70 years of age at time of 5-year surveillance colonoscopy interval
A baseline colonoscopy with a finding of 1-2 small tubular adenomas and are due for their 5-year surveillance procedure in 2022
Average risk for CRC
A valid mailing address, account (i.e., KPNC's secure messaging portal), and telephone number at time of study enrollment

Exclusion Criteria

More than 12 months of membership prior to index colonoscopy, and indications that would make an individual above average risk for CRC, such as: adenoma with advanced histology on colonoscopy, adenoma >10 mm on colonoscopy, family history of CRC, prior history of colonoscopy, prior history of adenomas or colon polyp diagnoses, history of IBD, history of hereditary polyposis syndrome, 3 or more adenomas, adenoma 10 mm in size or greater, adenoma with advanced histology, and any sessile serrated polyp or traditional serrated adenoma
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