Improving Appetite Regulation in Patients With Obesity

    Not Recruiting
  • End date
    Feb 28, 2023
  • participants needed
  • sponsor
    University of North Carolina, Chapel Hill
Updated on 14 September 2022
overweight or obesity
Accepts healthy volunteers


Over 70% of U.S. adults have overweight or obesity. Currently, the most efficacious behavioral intervention for obesity is standard behavioral treatment (SBT), often composed of group sessions, calorie goals, and physical activity goals. With this approach, participants often lose 8-10% of the person's baseline weight, and also decrease risk for cardiovascular disease. Long-term weight loss, however, is limited; many participants return to baseline weight within five years following treatment. One reason SBT may not create long-term weight loss may be due to treatment components that teach participants to rely on external methods for changing eating decisions (e.g., counting calories, restricting certain foods), rather than internal cues of hunger and satiety. Because individuals with obesity report significant challenges with adhering to these cues, augmenting behavioral interventions with appetite self-regulation training may be a solution. Thus, the investigator propose to examine the feasibility and acceptability of a 6-month remotely-delivered appetite regulation + lifestyle modification intervention to treat obesity.


Aim 1. Using a single-arm design, the investigator will examine the feasibility and acceptability of a 6-month, remotely-delivered, appetite self-regulation intervention for weight loss maintenance.

Aim 2. Examine the preliminary efficacy of the intervention on weight maintenance at 4 and 6 months.

Condition Weight Loss, Weight Gain Prevention, Obesity
Treatment Appetite Self-Regulation Intervention
Clinical Study IdentifierNCT05200520
SponsorUniversity of North Carolina, Chapel Hill
Last Modified on14 September 2022

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