Fructose Effect on Neuroinflammation and Feelings (MOODYFRUCTOSE)

  • participants needed
  • sponsor
    University Hospital, Rouen
Updated on 16 August 2022
Accepts healthy volunteers


Fructose is increasingly present in our food. The increase in its consumption is associated with the increase in the prevalence of several pathologies such as metabolic syndrome or hepatic steatosis. The effect of fructose consumption on brain health has been poorly studied. Studies in animal models show that diets enriched in fructose promote the development of emotional behavior disorders. Fructose malabsorption is also associated with changes in the microbiota that could also impact brain health. However, no human study to date has associated fructose malabsorption with changes in the gut microbiota and effects on brain health.

The objective of this study is to study the emotional behavior of a population of healthy volunteers according to the presence or not of fructose malabsorption. Patients with fructose malabsorption are susceptible to gut dysbiosis without necessarily consuming high amounts of fructose.

Condition Gastro-Intestinal Disorder
Treatment Fructose respiratory test
Clinical Study IdentifierNCT05371067
SponsorUniversity Hospital, Rouen
Last Modified on16 August 2022

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