Evaluation of the Change in the DA Ratio, IR and SSI as Parameters of Corneal Biomechanics Post Different LVC Procedures

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  • participants needed
  • sponsor
    Cairo University
Updated on 4 October 2022
Accepts healthy volunteers


In the study, The Investigators will compare the participates' corneal biomechanical properties including:

Deformation Amplitude ratio (Da Ratio) Integrated Radius (IR) Stress strain index (SSI)

All measurements will be taken before and after 3 months of LVC.


Each Participant will undergo preoperative pentacam and corvis scan for his eyes and the 3 months post operative.

The participants are divided into 3 groups, one who underwent LASIK, one PRK and one Femto LASIK.

Collected data will before and after surgery will be compared in each arm and then the 3 arms will be compared together.

Condition Corneal Biomechanics
Treatment CORVIS
Clinical Study IdentifierNCT05377099
SponsorCairo University
Last Modified on4 October 2022


Yes No Not Sure

Inclusion Criteria

• Age range 18 - 40 years
Normal eyes with normal tomographic indices
Patients with maximum mean refractive spherical equivalent (MRSE) of -7.00 diopters and with maximum astigmatism of -3.00 diopters

Exclusion Criteria

• Patients with any other coexisting corneal diseases
Keratoconus eyes
Eyes with previous refractive corneal surgery
Patients with increased intraocular pressure
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How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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