A Double-Blind, Placebo-Controlled Phase 2b Study to Evaluate the Efficacy and Safety of ARO-APOC3 in Adults with Severe Hypertriglyceridemia

  • sponsor
    Arrowhead Pharmaceuticals
Updated on 27 May 2022


If you have triglycerides greater than 150 mg/dL you may qualify for this study involving an investigational (new) subcutaneous (just under the skin) injection.


These studies involve about 17 visits over the course of 54 weeks. There are 2 study injections for those who qualify. If you qualify you will be paid $75 for each study visit completed. If you choose to participate in an optional blood collection sub-study, you will be paid $250.00 per collection visit, if you qualify.

Condition Elevated Triglycerides (Hypertriglyceridemia)
Clinical Study IdentifierTX300406
SponsorArrowhead Pharmaceuticals
Last Modified on27 May 2022


Yes No Not Sure

Inclusion Criteria

Older than 18 years old
History of Triglycerides greater than 150 mg/dL

Exclusion Criteria

Active pancreatitis
Planned bariatric surgery or similar weight loss procedures
Planned cardiovascular surgery/intervention
HIV+, active Hepatitis
Cancer within the past 2 years (except certain skin, cervical or bladder cancers)
unwilling to limit alcohol consumption to less than 14 drinks per week
Clear my responses

How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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