Background: Mucosal bleeding is the most frequent complication with endoscopic nasal surgeries, as it interferes with the optimal visualization of the intranasal anatomy, leading to increased risk of complications, increased operation time, and increased blood loss. There are several pharmacological techniques for the appropriate control of intraoperative bleeding.
Objectives: To compare the safety and efficacy of oral labetalol versus oral metoprolol as a premedication for controlled hypotensive anesthesia during endoscopic nasal surgeries.
Patients and Methods: This is a randomized, double-blind, phase four, comparative clinical trial; carried out on 60 patients, who were candidates for endoscopic nasal surgeries under general anesthesia at our hospital. Patients were randomly allocated into two equal groups; group L, received oral labetalol, and group M, received oral metoprolol.
| Condition | Hypotension Drug-Induced |
|---|---|
| Treatment | Metoprolol Tartrate Oral Tablet, Labetalol Hydrochloride Oral Tablet |
| Clinical Study Identifier | NCT05368376 |
| Sponsor | Damanhour Teaching Hospital |
| Last Modified on | 3 July 2022 |
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