A Study Evaluating Safety, PK, and Efficacy of Tafasitamab and Parsaclisib in Participants With Relapsed/Refractory Non Hodgkin Lymphoma (R/R NHL) or Chronic Lymphocytic Leukemia (CLL) (topMIND)

  • STATUS
    Not Recruiting
  • End date
    Nov 6, 2023
  • participants needed
    100
  • sponsor
    Incyte Corporation
Updated on 14 September 2022
chronic lymphocytic leukemia
lymphoma
leukemia
btk inhibitor
anti-cd20 antibody
cyclin d1

Summary

The purpose of this single-arm, open-label, Phase 1b/2a, multicenter basket study is to evaluate whether tafasitamab and parsaclisib can be safely combined at the recommended Phase 2 dose (RP2D) and dosing regimen that was established for each of the 2 compounds as a treatment option for adult participants with R/R B-cell malignancies.

Details
Condition Chronic Lymphocytic Leukemia, Non Hodgkin Lymphoma
Treatment Parsaclisib, Tafasitamab
Clinical Study IdentifierNCT04809467
SponsorIncyte Corporation
Last Modified on14 September 2022

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