Study Comparing Local/ MAC Anesthesia in Lumbar Decompression

  • STATUS
    Recruiting
  • End date
    Dec 25, 2028
  • participants needed
    100
  • sponsor
    Stanford University
Updated on 25 May 2022

Summary

Explore efficacy, complications, and other factors associated with anaesthetic choice- To evaluate the efficacy of local + MAC as an alternative anesthetic to general anesthesia and to analyze patients' outcomes and experiences.

Description

100 Patients ages 40-95 with lumbar stenosis to be decompressed are randomized to undergo the procedure with either general anesthesia or local anesthetic with MAC.

Participants will be randomized to either group 1 General anesthesia or group 2 Local + MAC anesthetic group.

Group 1: General Anesthesia: Medically induced unconsciousness that suppresses reflexes and requires intubation (a tube inserted through the mouth and into the airway) to assist in breathing.

Group 2: Local + MAC: Local anesthetic (lidocaine) injected into the site of the incision/dissection with additional IV medication (Propofol) to achieve a state in which the patient is generally aware, but relaxed

Details
Condition Lumbar Spinal Stenosis
Treatment Lidocaine Hydrochloride, Injectable, Propofol Injection
Clinical Study IdentifierNCT04992572
SponsorStanford University
Last Modified on25 May 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

Patients with lumbar stenosis to be decompressed over 1-3 segments
Ages 40-95
Appropriate for general anesthesia

Exclusion Criteria

Planned significant nerve root retraction
Previous fusion operation
Unable to comply with follow up
Patients with daily morphine equivalents or more 100mg
Patients with a known hypersensitivity to propofol or any of DIPRIVAN Injectable Emulsion components
Patients with allergies to eggs, egg products, soybeans or soy products
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