Physiological Effects of HFNC During Exercise in Patients With Fibrosing Interstitial Lung Diseases (HighFlowMusc)

  • End date
    Apr 10, 2024
  • participants needed
  • sponsor
    ADIR Association
Updated on 23 May 2022


in this study, the investigators aim to describe the effects of highflow nasal canulae oxygen therapy (HFNC) on respiratory muscle function during exercise in patients with fibrosing interstitial lung diseases (ILD) during an endurance test

Condition Interstitial Lung Disease, Pulmonary Rehabilitation
Treatment high flow nasal canulae, Ventury mask
Clinical Study IdentifierNCT05372926
SponsorADIR Association
Last Modified on23 May 2022


Yes No Not Sure

Inclusion Criteria

Cared for as part of a respiratory rehabilitation program (ADIR association)
Presenting diffuse fibrosing interstitial pneumonitis, documented by CT scan data and whatever its etiology
Presenting severe hypoxemia in ambient air (SpO2<90%) during an exercise test (6-minute walk test or functional exercise test)

Exclusion Criteria

Patient with a contraindication to carrying out a respiratory rehabilitation program
Patient having presented an exacerbation of PID, pneumothorax or pneumomediastinum in the 3 months preceding potential inclusion
Tracheostomized patient
Patient with a contraindication to the placement of a nasogastric tube
Pregnant or breastfeeding women or women of childbearing age without effective means of contraception (a pregnancy test will be carried out)
Protected adult patient (guardianship or curatorship)
Patient deprived of liberty by court or administrative decision
Refusal of patient participation or consent
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