EX9536-4773: Effect of Semaglutide 2.4 mg once-weekly on function and symptoms in subjects with obesity related heart failure with preserved ejection fraction, and type 2 diabetes

    Not Recruiting
Updated on 3 December 2022
ejection fraction
hemoglobin a1c


This study will look at how participants' daily life is affected by their heart failure. The study will also look at the change in participants' body weight.


This study will compare the effect of semaglutide (a new medicine) compared to "dummy" medicine on body weight and heart failure symptoms.
Participants will either get semaglutide or "dummy" medicine, which treatment participants get is decided by chance.
Participants will need to take 1 injection once a week. The study medicine is injected with a thin needle in a skin fold in the stomach area, thigh or upper arm.
During the study participants will have talks with the study staff about healthy lifestyle and physical activity.
The study will last for about 59 weeks, that is a little more than 1 year. Participants will have 12 clinic visits with the study doctor

Condition Heart Failure, Diabetes Mellitus Types I and II
Clinical Study IdentifierTX299754
Last Modified on3 December 2022

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