Compression Ultrasonography in Non-high Probability of Deep Vein Thrombosis (EPREVUP)

  • End date
    Feb 28, 2025
  • participants needed
  • sponsor
    University Hospital, Strasbourg, France
Updated on 4 October 2022
deep vein thrombosis
deep venous thrombosis of lower extremity


Compression ultrasound is commonly used in emergency department. Accuracy to rule out deep vein thrombosis is excellent but lower then Ddimer assessment which is actually gold standard. With progress in formation of emergency physicians (EP), quality of material used, the investigators hypothesize that compression ultrasound can rule out deep vein thrombosis in case of non high probability, as standard care and DDimer assay.

Condition Deep Vein Thrombosis
Treatment compression ultrasound
Clinical Study IdentifierNCT04917328
SponsorUniversity Hospital, Strasbourg, France
Last Modified on4 October 2022


Yes No Not Sure

Inclusion Criteria

adult patient
Patient presenting to the emergency department with clinical suspicion of DVT (i.e. pain and/or lower extremity edema)
Patient with a non-high probability according to the modified Wells score, i.e. a score of 0 or 1
Subject with a social health insurance plan
Subject able to understand the objectives and risks of the research and to give a signed and dated informed consent

Exclusion Criteria

Patient with suspected pulmonary embolism
Patient with a high probability of DVT
Impossible to perform a whole leg doppler ultrasound within 5 days
Pregnant or breast-feeding woman, on patient's declaration
Subject under court protection
Subject under guardianship or curatorship
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