This is a clinical study to investigate the safety, tolerability and immunogenicity of a
VLA2001 booster vaccination in participants aged 18 years and older. In total approximately
275 participants are planned to be enrolled.
This is a multicentric, open-label, phase 2/3 study to investigate the safety, tolerability
and immunogenicity of a VLA2001 booster vaccination standard dose in adults aged ≥18 to ≤50
years or double dose in volunteers aged >50 years.
Volunteers who are either generally healthy or are with a stable medical condition will be
enrolled. In total approximately 275 participants are planned to be enrolled. It is planned
to enroll approximately 25% of participants who are above 65 years into the cohorts with
participants above 50 years of age.
Immunogenicity and safety will be assessed up to Month 12 after the booster vaccination.
If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.
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