Effect of Multiple Perforations of the Sinus Floor on Bone Formation After Sinus Floor Elevation

  • STATUS
    Recruiting
  • End date
    Dec 24, 2027
  • participants needed
    12
  • sponsor
    Medical University of Vienna
Updated on 24 May 2022
Accepts healthy volunteers

Summary

The aim of the present study is to compare the rate of new bone formation after sinus floor elevation with or without perforation of the cortical sinus floor prior to insertion of augmentation material. Twelve patients requiring bilateral sinus floor elevation will be recruited for a pilot study in split-mouth design. On both sides a lateral window will be prepared and the sinus mucosa will be elevated. After this step, the sides are assigned as test or control side. While the control side is just filled with augmentation material, an additional step is performed for the test side, i.e., prior to inserting the augmentation material, the cortical bone layer of the sinus floor is perforated several times into the trabecular bone layer to improve the blood supply to the grafting material. Thereafter, both sides are left to healing for 4-6 months until implant installation. At timepoint of implant installation, a bone biopsy will be collected to allow histological assessment of the grafted area.

Details
Condition Sinus Elevation, Dental Implant, Bone Formation
Treatment perforation of the sinus floor, no perforation of the sinus floor
Clinical Study IdentifierNCT05362136
SponsorMedical University of Vienna
Last Modified on24 May 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

in need of bilateral sinus floor elevation
residual alveolar ridge height 2-6mm
residual alveolar ridge width > 4mm

Exclusion Criteria

uncontrolled periodontal disease
acute or chronic sinusitis
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