Appalachian Partnership to Reduce Disparities (Aim 2)

  • End date
    May 11, 2025
  • participants needed
  • sponsor
    Wake Forest University Health Sciences
Updated on 11 April 2023
Accepts healthy volunteers


By combining two strategies (i.e., peer navigation and mHealth) into a complete, culturally compatible, bilingual intervention to increase the use of needed HIV, STI, and HCV prevention and care services among racially/ethnically diverse GBMSM and transgender women in rural Appalachia.

Study Investigators anticipate that participants in the intervention group, relative to counterparts in the delayed-intervention group, will demonstrate increased HIV, STI, and HCV testing.


This CBPR study will advance prevention science and practice through testing an innovative intervention to promote and support the use of needed HIV, STI, and HCV prevention and care services among GBMSM and transgender women; and developing priorities and recommendations to improve their health that will be disseminated to inform public health practice, research, and policy. By integrating peer navigation and mHealth strategies, the proposed study provides a unique opportunity to improve health among vulnerable, hidden, and neglected populations living in rural Appalachia. Findings from this research may inform strategies and approaches to address other health disparities in other rural populations.

Condition HIV/AIDS, STI, HCV
Treatment mHealth, Peer Navigation
Clinical Study IdentifierNCT04378439
SponsorWake Forest University Health Sciences
Last Modified on11 April 2023


Yes No Not Sure

Inclusion Criteria

reside in one of the rural Appalachian catchment countiesreside in one of the rural Appalachian catchment counties
be ≥18 years of age
report being assigned male sex at birth and having had sex with at least 1 man in past 12 months
provide informed consent
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How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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