Fosaprepitant , Tropisetron and Olanzapine for the Prevention of Nausea and Vomiting in Patients With Breast Cancer
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- STATUS
- Recruiting
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- End date
- Jun 1, 2024
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- participants needed
- 403
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- sponsor
- Henan Cancer Hospital
Summary
Standard antiemetic therapy without dexamethasone for the prevention of nausea and vomiting in patients with breast cancer
Description
This is a multicenter, randomized, controlled, open-label, phase III study assessing the efficacy and safety of fosaprepitant, tropisetron and olanzapine for the Prevention of Nausea and Vomiting in Patients With Breast Cancer Receiving Anthracycline/Cyclophosphamide-containing Chemotherapy. Eligible patients will be randomized to receive either standard antiemetic therapy (fosaprepitant, tropisetron, dexamethasone and olanzapin) or standard antiemetic therapy without dexamethasone in a 1:1 ratio.
Details
| Condition | Chemotherapy-induced Nausea and Vomiting |
|---|---|
| Treatment | Fosaprepitant , Tropisetron and Olanzapine, Fosaprepitant , Tropisetron, Dexamethasoneand Olanzapine |
| Clinical Study Identifier | NCT05242874 |
| Sponsor | Henan Cancer Hospital |
| Last Modified on | 3 May 2022 |
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