Coronary and Heart Effects of Early Treatment in Familial Hypercholesterolemia (CHEETAH)

  • End date
    Feb 1, 2023
  • participants needed
  • sponsor
    Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Updated on 10 May 2022
Accepts healthy volunteers


This study evaluates plaque burden and characteristics in early-treated FH patients compared to late-treated FH patients and healthy individuals.

Condition Familial Hypercholesterolemia
Treatment Coronary Computed Tomography Angiography (CCTA)
Clinical Study IdentifierNCT05352386
SponsorAcademisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Last Modified on10 May 2022


Yes No Not Sure

Inclusion Criteria

Diagnosed with heterozygous familial hypercholesterolemia or non FH-control
Adult patients between 25 and 55 years old

Exclusion Criteria

Renal insufficiency, defined as eGFR < 30 ml/min
Atrial fibrillation
Any other treatment or clinically relevant condition that could interfere with the conduct or interpretation of the study in the opinion of the investigator
Inability or unwillingness to comply with the protocol requirements, or deemed by investigator to be unfit for the study
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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