Targeting Microbiota in Female Overactive Bladder Syndrome

  • STATUS
    Recruiting
  • End date
    Nov 30, 2024
  • participants needed
    100
  • sponsor
    Medical University of Vienna
Updated on 6 May 2022
overactive bladder syndrome
Accepts healthy volunteers

Summary

The aim of this study is to compare the urinary viral microbiome and bacterial microbiome between overactive bladder syndrome (OAB) patients and healthy controls in order to determine a possible alteration in the urinary microbiome which may predispose women for OAB, and also in order to determine a possible influence of the urinary viral microbiome on the urinary bacterial microbiome which may predispose the individual to OAB. Furthermore, we aim to compare the urinary bacterial microbiome to the vaginal, rectal, urethral and salivary bacterial microbiome within the same individual and between the two groups in order to determine a possible route of colonization of the urinary bladder.

Details
Condition Microbiota, Urinary Bladder, Overactive
Clinical Study IdentifierNCT05328011
SponsorMedical University of Vienna
Last Modified on6 May 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

without symptoms of overactive bladder or any other form of lower urinary
tract symptoms
Age-matched to case group (+/- 5 years)
BMI-matched to case group (18,5- 24,9 kg/m2 normal weight; 25- 29,9 kg/m2 overweight; 30- 34,9 kg/m2 obesity grade I)

Exclusion Criteria

As case group plus any form of lower urinary tract symptoms including OAB
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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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