Immuno-epidemiological and Socio-behavioral Evaluation of Release of Sterile Male Aedes Albopictus Mosquitoes on Human-vector Contacts (EXPOCAP)

  • STATUS
    Recruiting
  • End date
    Jun 19, 2023
  • participants needed
    500
  • sponsor
    Institut de Recherche pour le Developpement
Updated on 19 April 2022
Accepts healthy volunteers

Summary

This trial is based on 2 complementary components, named ExpAlbo Biomarker and CAPAlbo Questionnaire

  1. ExpAlbo Biomarker (Exposure to the Aedes albopictus mosquito): This component concerns the epidemiological evaluation of the effectiveness of the release of sterile male mosquitoes on the level of exposure of individuals to the bites of the tiger mosquito through the use of a new immunological biomarker of the human-vector contact, developed over the past 20 years by the IRD-MIVEGEC team. Indeed, when a person is bitten by a mosquito, he or she develops a defence reaction, called an immune reaction, against the mosquito's saliva. The main objective of this study is to measure this immune response, and more specifically the antibody response specifically directed against compounds (peptide = small fragment of a protein) in mosquito saliva, and to determine whether this anti-saliva antibody response, and therefore exposure to mosquito bites, decreases when the mosquito control strategy is applied.
  2. CAPAlbo Questionnaire: This component is concerned with assessing the impact of sterile male mosquito releases on perceptions and practices related to exposure to Aedes albopictus based on population-based questionnaire surveys. The main objective of these surveys is to determine whether changes in objective exposure to Aedes albopictus mosquitoes are associated with changes in the perception of the nuisance and in the lifestyle habits of respondents, particularly those related to the prevention of mosquito bites (such as the use of repellents or mosquito nets).

Details
Condition Mosquito Bite
Treatment sterile insect technique (TIS)
Clinical Study IdentifierNCT05313126
SponsorInstitut de Recherche pour le Developpement
Last Modified on19 April 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

To inhabit on a regular basis in the intervention/control area
To speak French
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