Last updated on October 2006

Testosterone Replacement in Middle-Aged Hypogonadal Men With Dysthymia: Parallel Group Double Blind Randomized Trial

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Dysthymic Disorder
  • Age: Between 40 - 80 Years
  • Gender: Male
  • Other:
    Male, age 40-80 years.
    Diagnosed with hypogonadism (total T level below 350 ng/dl), but not previously
    Diagnosis of Dysthymic disorder with onset after age 40.
    PSA < 4.0.
    Normal digital exam of the prostate in the preceding 1 year.
    For subjects currently taking an antidepressant: Current antidepressant treatment
    last 6 weeks or longer, with decent dose and with no remission (or with partial
    remission only HAM-D > 12).
    Able to give informed consent.

You may not be eligible for this study if the following are true:

  • Acute, severe, or unstable prostatitis, symptomatic prostatic hypertrophy,
    polycythemia, severe acne, breast cancer, prostate cancer, or hypopituitarism.
    Currently being treated with testosterone.
    Meets lifetime criteria for schizophrenia, schizoaffective disorder, any bipolar
    disorder (i.e., BP-I, BP-II, or BP NOS); or a major depressive episode in the
    preceding 5 years.
    Current suicidal risk.
    Current (past year) substance abuse or dependence.

Recruitment Status: Open

Brief Description Eligibility Contact Research Team

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