Reducing Pain and Opioid Use With CBD
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- STATUS
- Recruiting
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- End date
- Feb 21, 2027
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- participants needed
- 150
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- sponsor
- University of Colorado, Denver
Summary
This is a double-blind, placebo-controlled, parallel group study designed to assess the tolerability and efficacy of fsCBD and bsCBD, compared to a placebo control, to reduce opioid use, anxiety, and pain and improve sleep and cognitive function. If eligible for the study, subjects will be randomized to receive one of the conditions for 12 weeks.
Description
To better understand the effects of hemp-derived CBD with and without a small amount of THC, we propose a Phase II randomized clinical trial (RCT) to examine the safety, tolerability, and clinical effects of Full Spectrum CBD (fsCBD, contains less than 0.3% THC) vs. Broad Spectrum CBD (bsCBD, does not contain THC), vs. a matching placebo in a population of opioid users.
This is a double-blind, placebo-controlled, parallel group study designed to assess the tolerability and efficacy of fsCBD and bsCBD, compared to a placebo control, to reduce opioid use, anxiety, and pain and improve sleep and cognitive function. If eligible for the study, subjects will be randomized to receive one of the conditions for 12 weeks.
The initial Week 0 / Baseline visit will take place at the University of Colorado Anschutz Medical Campus. There will be in-person visits at Weeks 1, 6, and 12. Participants will be contacted by Zoom each remaining week during the 12-week period. A follow up Zoom interview will occur in Week 16, approximately 4 weeks after the end of dosing.
Details
| Condition | Opioid Use Disorder |
|---|---|
| Treatment | Placebo, Cannabidiol |
| Clinical Study Identifier | NCT05299944 |
| Sponsor | University of Colorado, Denver |
| Last Modified on | 21 April 2022 |
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.
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Learn moreComplete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.
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