Contribution of L-Tyrosine to Human Decision Making in Stressful Situations (TYRO-STRESS)

  • participants needed
  • sponsor
    Direction Centrale du Service de Santé des Armées
Updated on 28 January 2023
Accepts healthy volunteers


L-tyrosine is a chemical precursor of dopamine. Under specific conditions, tyrosine administration can increase brain dopamine levels and therefore several studies have explored whether tyrosine supplementation can have a beneficial effect on cognitive and behavioural performance that is dependent on dopaminergic function. However, the effects of tyrosine supplementation are mixed: some studies show positive effects while others do not. Stress leads to an increase in dopaminergic activity and turnover in the brain, resulting in a decrease in brain dopamine levels. We propose to study the contribution of tyrosine to decision making and more particularly to the processes of response selection (mediated by the prefrontal cortex and under the influence of the dopaminergic system) in stressful situations.

Condition Stress, Psychological
Treatment Placebo, Blood Collection, cognitive tasks, Electroencephalography (EEG), Electromyography (EMG), L-Tyrosine 500 Mg, Stress exposure, Anxiety scale
Clinical Study IdentifierNCT04518254
SponsorDirection Centrale du Service de Santé des Armées
Last Modified on28 January 2023

Similar trials to consider


Browse trials for

Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer

user name

Added by • 



Reply by • Private

Lorem ipsum dolor sit amet consectetur, adipisicing elit. Ipsa vel nobis alias. Quae eveniet velit voluptate quo doloribus maxime et dicta in sequi, corporis quod. Ea, dolor eius? Dolore, vel!

  The passcode will expire in None.

No annotations made yet

Add a private note
  • abc Select a piece of text from the left.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.
Add a private note