Effect of Physiotherapy in Patients Presenting to the Emergency Department With Nonspecific Lower Back Pain (EPAC-II)

  • End date
    Dec 8, 2022
  • participants needed
  • sponsor
    University Hospital, Basel, Switzerland
Updated on 8 June 2022
back pain
low back pain


Physiotherapy is a long established therapy in lower back pain. It is unknown if physiotherapeutic interventions in patients presenting to the Emergency Department (ED) with nonspecific lower back pain are beneficial. The aim of this study is to assess whether patients presenting to the emergency department with non-specific low risk low back pain would benefit from a physiotherapy intervention, as compared to patients without physiotherapy intervention at time of ED presentation.

Condition Lower Back Pain
Treatment Physiotherapeutic intervention
Clinical Study IdentifierNCT05156957
SponsorUniversity Hospital, Basel, Switzerland
Last Modified on8 June 2022


Yes No Not Sure

Inclusion Criteria

Written informed consent
Experiencing nonspecific lower back pain
Presentation to the Emergency Department (ED) of the University Hospital Basel

Exclusion Criteria

Inpatient disposition after ED work-up
Red Flags" at time of ED-presentation
Major trauma in all patients
Fractures leading to immobilization
Severe or progressive sensory alteration or weakness
Bladder or bowel dysfunction
Evidence of neurological deficit on physical examination
Severe chronic disease, such as metastasized cancer, palliative care
Epidural steroid injections in the last 3 months
Inability or contraindications to undergo the investigated intervention or to follow the study procedures, e.g. due to certain neurological disorders, language problems, psychological disorders, cognitive impairment, physical inability etc
Prior enrolment in this trial
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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