Peripherel Perfusion Index to Predict Sepsis in Very Low Birth Weight Infants

  • End date
    Dec 31, 2022
  • participants needed
  • sponsor
    Children's Hospital of Fudan University
Updated on 25 March 2022


To explore the predictive value of peripheral perfusion index in late onset sepsis of very low birth weight infants , obtain the threshold by observing the perfusion index of very low birth-weight infants within one month after birth, this value can be used as a threshold to predict late onset sepsis in very low birth weight infants.


From the day the very low birth weight infant was admitted to hospital, monitoring was recorded once a day, and continuous monitoring was recorded for 1 month. Before collection, the infant was confirmed to be in supine position with neutral temperature, and at the same time, the infant was in a quiet state, without the contact and operation of medical personnel. This study will first use LMS curve to fit the trend of perfusion index in very low birth weight infants within one month after birth.The perfusion index threshold of the outcome index was determined by ROC curve.

Condition VLBW - Very Low Birth Weight Infant
Treatment Not applicable (cohort study)
Clinical Study IdentifierNCT05224921
SponsorChildren's Hospital of Fudan University
Last Modified on25 March 2022


Yes No Not Sure

Inclusion Criteria

Infants weighting <1500g
Infants admitted to Children's Hospital of Fudan University
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