MRI-Eye Tracking Pairing, a Tool for Assessing Social Cognition in Children With ASD (IRM-ET)

  • STATUS
    Recruiting
  • End date
    May 25, 2024
  • participants needed
    68
  • sponsor
    Centre Hospitalier Universitaire, Amiens
Updated on 25 March 2022
Accepts healthy volunteers

Summary

Most studies use static visual percepts that are less representative of joint attention versus an ecological environment. This has the consequence of decreasing the perception of an interaction with a social partner, which is an essential step in achieving joint attention. The originality of this study is to improve the design of visual percepts (in the form of video) in order to mimic an ecological environment as much as possible by using MRI-ET coupling. The second originality of this study is the longitudinal exploration of the neurodevelopment of social cognition in autistic children. Studies by the Redcay and Oberwelland teams observe different activations at different ages. The hypothesis is that the perception of joint attention varies over time in people with ASD. To date, there are no studies to determine the influence of childhood neurodevelopment in autistic people on the perception of joint attention. It would be unprecedented to use the MRI-ET pairing as a tool for assessing social cognition as a function of the development of children with ASD.

Details
Condition ASD, Functional Magnetic Resonance Imaging, Eye Tracking, Social Cognition, Joint Attention
Treatment MRI-ET
Clinical Study IdentifierNCT05194254
SponsorCentre Hospitalier Universitaire, Amiens
Last Modified on25 March 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

For the group of people with Autism Spectrum Disorders (experimental group)
Age between 10 to 20 years old
Diagnosis of ASD (CARS) ≥ 30 performed at inclusion
IQ test evaluation (regardless of the result) performed by a trained psychologist
Obtaining informed oral and written consent after appropriate information
Obtaining informed oral and written consent from the legal guardian after information
Be affiliated with social security
No contraindication to magnetic resonance imaging
For the TD (Typical Development) group of people (control group)
Age between 10 to 20 years old
Diagnosis of ASD (CARS) <30 performed at inclusion
IQ test evaluation (regardless of the result) performed by a trained psychologist
Obtaining informed oral and written consent after appropriate information
Obtaining informed oral and written consent from the legal guardian after information
Be affiliated with social security
No contraindication to magnetic resonance imaging

Exclusion Criteria

For all groups
Age outside the range 10 to 20 years
Person with a contraindication to MRI (including claustrophobia, pace maker, neurosurgical clips, vascular clips, heart valves, ventriculoperitoneal valves, cochlear implant, neurostimulator, intraocular metal shards, joint prosthesis, etc.)
Person suffering from major obesity (> 140 kg) not allowing him to enter the tunnel of the MRI machine (diameter <70cm)
Pregnant or breastfeeding woman
Person under guardianship or guardianship or deprived of liberty by a judicial or administrative decision
For TD people (control group)
Person with psychiatric disorders such as attention disorder with or without hyperactivity, depression, bipolar disorder and schizophrenia
Person with a neurological history such as epilepsy and / or neurovascular accident
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