Letrozole in Induction of Abortion of Anembryonic Pregnancy

  • STATUS
    Recruiting
  • participants needed
    90
  • sponsor
    Cairo University
Updated on 1 July 2022

Summary

Some studies suggest the prescription of aromatase inhibitors prior to the use of misoprostol for inducing drug abortion. the aim of the study is to compare the effectiveness of various regimens of letrozole combined with misoprostol versus using misoprostol alone in inducing complete abortion in patients with blighted ovum.

Description

Some studies suggest prescription of aromatase inhibitors prior to the use of misoprostol for inducing drug abortion, increases the efficiency of the treatment regimen and also decreases the need for surgical interventions. Some conducted studies have mentioned reinforcing the impact of misoprostol with letrozole, but reaching the ideal dose still needs more studies, so in this study, the investigators will compare the effectiveness of various regimens of letrozole ( 10 mg/d for 3 days or a single dose of 20 mg) combined with misoprostol versus using misoprostol alone in inducing complete abortion in patients with a blighted ovum.

Details
Condition Anembryonic Pregnancy
Treatment Placebo Tablets, Letrozole Tablets, Misoprostol Tabets
Clinical Study IdentifierNCT05198050
SponsorCairo University
Last Modified on1 July 2022

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