An Observational Study of Risk Factors and Long-term Prognosis of Patients With Liver Abscess in the "Real-world"

  • End date
    Jan 1, 2025
  • participants needed
  • sponsor
    Nanfang Hospital of Southern Medical University
Updated on 4 October 2022


Pyogenic liver abscess is one of the most common visceral abscesses, its incidence is increasing worldwide. According to the previous literature, the mortality rate of pyogenic liver abscess is as high as 31% and become a serious social health problem. However, the data of prospective observational real-world studies are scarce and no relevant research of the liver histological change has been reported, so the long-term prognosis and the risk factors for pyogenic liver abscess are still unknown. Patients will be followed up prospectively for a period of 2 years and observed clinical prognosis (all-cause mortality, the recurrence rate, and the rehospitalization rate). The investigators will investigate the predictive value of clinical risk factors for clinical prognosis and establish clinical prediction models to predict the long-term prognosis of pyogenic liver abscesses.

Condition Liver Abscess, Pyogenic, Liver Abscess, Abscess, Infections
Clinical Study IdentifierNCT05213949
SponsorNanfang Hospital of Southern Medical University
Last Modified on4 October 2022


Yes No Not Sure

Inclusion Criteria

Patients older than 18 years of age
Irrespective of gender
Symptomatic patients of liver abscess confirmed with radiology imaging, either by ultrasonography or computed tomography scan

Exclusion Criteria

Patients <18 years old
Pregnancy at presentation
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