Atrial Fibrillation Patients Treated With Catheter Ablation

  • days left to enroll
  • participants needed
  • sponsor
    Peking Union Medical College Hospital
Updated on 12 March 2022
radiofrequency ablation
catheter ablation
atrial arrhythmia
paroxysmal atrial fibrillation
persistent atrial fibrillation
pulmonary vein isolation


This is a single-center prospective observational cohort study of atrial fibrillation patients treated with radiofrequency ablation.


The effect of radiofrequency therapy on the life quality and atrial function of atrial fibrillation patients will be assessed, through the multidimensional analysis of baseline clinical data, serological indicators of atrial fibrosis, echocardiography, cardiac magnetic resonance imaging, atrial potential mapping, life quality, and long-term ECG monitoring within 1 week after radiofrequency ablation. A predictive model for atrial fibrillation recurrence after ablation will be established. Based on the cross-sectional analysis of baseline data, the relationship between non-invasive assessment of atrial fibrosis (imaging and serology), atrial electrical activity, and atrial function will be analyzed as well, and atrial fibrillation patients with ventricular fibrosis will be selected for gene sequencing to explore the existence of underlying cardiomyopathy and provide data for further research.

Condition Atrial Fibrillation, Atrial Fibrillation Recurrent
Treatment Radiofrequency ablation
Clinical Study IdentifierNCT05266144
SponsorPeking Union Medical College Hospital
Last Modified on12 March 2022


Yes No Not Sure

Inclusion Criteria

Non-valvular atrial fibrillation, including paroxysmal atrial fibrillation and persistent atrial fibrillation
-80 years old
The anteroposterior diameter of the left atrium is less than 50mm via TTE
Patient meets the intervention criteria for bilateral pulmonary vein isolation after evaluation by electrophysiological specialists
Patient consents to ablation treatment

Exclusion Criteria

Intra-atrial thrombus detected by TEE
Previous radiofrequency ablation for atrial fibrillation
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