Laparoscopic IIeocecus-Sparing Right Hemicolectomy for Cancer of the Hepatic Flexure and Proximal Transverse Colon (LISH)

  • End date
    Sep 1, 2023
  • participants needed
  • sponsor
    Zhejiang University
Updated on 4 October 2022


To investigate whether laparoscopic ileocecus-sparing right hemicolectomy is feasible and oncologically safe


Our study is a single arm, single center clinical trial. The enrolled patients will accept laparoscopic ileocecus-sparing right hemicolectomy. The primary endpoint: postoperative complications, 1-year local recurrence. The second endpoint: conversion to conventional right hemicolectomy, time to first flatus after surgery, number of harvested lymph nodes, 3-year disease free survival, R0 resection, Specimen morphometry

Condition Hepatic Flexure Colon Cancer, Proximal Transverse Colon Cancer
Treatment laparoscopic ileocecus-sparing right hemicolectomy
Clinical Study IdentifierNCT04479111
SponsorZhejiang University
Last Modified on4 October 2022


Yes No Not Sure

Inclusion Criteria

Patients suitable for curative surgery 18-75years old
ASA grade I-III
Qualitative diagnosis: a pathological diagnosis of adenocarcinoma
Localization diagnosis: the tumor located at hepatic flexure and proximal transverse colon(proximal to the right branch of middle colic artery)
Enhanced CT scan of chest, abdominal and pelvic cavity: assessment of tumor stage is T1-T4N0 or TanyN+; there is no distant metastasis
Intraoperative measurement: the distance between colic branch of ileocolic artery and proximal edge of the tumor should be longer than 5cm
Informed consent

Exclusion Criteria

Simultaneous or metachronous multiple primary colorectal cancer
History of familial adenomatous polyposis, ulcerative colitis or Crohn's disease
Preoperative imaging examination results show: fused lymph node at the root of ileocolic artery
Distant metastasis
History of any other malignant tumor in recent 5 years
Patients need emergency operation
Not suitable for laparoscopic surgery (i.e., extensive adhesion caused by abdominal surgery, not suitable for artificial pneumoperitoneum, etc)
Informed consent refusal
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