Exercise Testing in Diseases and Health

  • End date
    Dec 30, 2025
  • participants needed
  • sponsor
    The Baruch Padeh Medical Center, Poriya
Updated on 13 April 2022
Accepts healthy volunteers


Cardiopulmonary exercise test (CPET) is a helpful tool for evaluation of aerobic exercise capacity and tolerance for variety of population. CPET provides a full assessment of the physiologic responses of the pulmonary, cardiovascular, muscular, and cellular oxidative systems to exercise. The test progression include a incremental stepwise (on treadmill) or ramp control protocol (on bike ergometer ) to exhaustion. Measurement of respiratory gas exchange i.e. oxygen uptake, carbon dioxide, minute ventilation, other variables while monitoring ECG, blood pressure, pulse oximetry and exertion perceived (Borg Scale) during an incremental test .

Aim: To compere exercise responses for maximal exercise testing with different population.


Each participants will conducted an exercise test on treadmill using Modified Bruce Protocol) or cycle ergometer. Quark CPET metabolic cart (Cosmed, Rome, Italy) will be use to collect and analysis gas exchange. 10 minute after the graded exercise test Supra maximal exercise test (SMT) will be done for 2 minutes one stage (treadmill protocol) or 10% at cycle protocol higher than highest load achieved in the incremental test.

all outcome measurement will be collected. Exercise tolerance and responses will be assess using the data of : pulmonary gas exchange; cardiovascular performance, and skeletal muscle metabolism.

Condition Exercise Test
Treatment Maximal exercise test
Clinical Study IdentifierNCT05263687
SponsorThe Baruch Padeh Medical Center, Poriya
Last Modified on13 April 2022


Yes No Not Sure

Inclusion Criteria

Patient who invited to the clinic to do incremental maximal exercise test or healthy
Participants with no known significant health problems

Exclusion Criteria

Acute fever
Acute myocardial infarction within 2 to 3 days
Unstable angina not previously stabilized by medical therapy
Uncontrolled cardiac arrhythmias causing symptoms or hemodynamic compromise
Symptomatic severe aortic stenosis
Uncontrolled symptomatic heart failure
Inability to perform exercise Orthopedic impairment severely compromising exercise
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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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