Usefulness of Video-Based Intervention in Helping Participants Encourage Their Families to Get Tested for BRCA Gene Mutations

  • End date
    Dec 31, 2023
  • participants needed
  • sponsor
    Ohio State University Comprehensive Cancer Center
Updated on 11 March 2022
Accepts healthy volunteers


This trial studies how well a video-based intervention works in helping participants encourage their families to get tested for BRCA gene mutations. Testing in families with BRCA gene mutations can allow for risk management and reduction with the overall goal of reducing cancer burden. Video-based intervention sent via text messages may help participants easily share information about BRCA gene mutations with family members.



I. To understand whether the use of a video-based message to encourage cascade testing, delivered via short message service (SMS) (text message) or shared on social media, is superior to a written message as a method of information-sharing among families that have BRCA gene mutations.

OUTLINE: Participants are randomized to 1 of 2 arms.

ARM A: Participants receive a 2-minute information-graphic video via text message consisting of misconceptions and issues that may be paramount when discussing mutation status with relatives that they can share with family via text message, email, or social media.

ARM B: Participants receive family letter via U.S. postal service mail consisting of misconceptions and issues that may be paramount when discussing mutation status with relatives.

Condition BRCA1 Gene Mutation, BRCA2 Gene Mutation
Treatment informational intervention, survey administration
Clinical Study IdentifierNCT05264532
SponsorOhio State University Comprehensive Cancer Center
Last Modified on11 March 2022


Yes No Not Sure

Inclusion Criteria

Individuals who test positive for mutations in BRCA1 or BRCA2 are eligible for this study
Family members who receive the video message/family letter will be invited to participate
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