Olfactory Change After Chemo-radiotherapy for Nasopharyngeal Carcinoma

  • participants needed
  • sponsor
    Sun Yat-sen University
Updated on 29 January 2023
induction chemotherapy
chemotherapy regimen
nasopharyngeal carcinoma


This is an observational cohort study aimed to explore the changes of olfactory function at multiple time points from baseline to 1 year after radiotherapy among the local advanced nasopharyngeal carcinoma patients.


Newly-diagnosed patients with stage III or IV non-metastatic Nasopharyngeal Carcinoma (AJCC 8th) will be recruited. Olfactory function of consecutive patients with nasopharyngeal carcinoma was assessed prospectively before treatment and serially up to 1 year after radiotherapy by the Sniffin' Sticks olfactory function test and by The Questionnaire of Olfactory Disorders (QOD) as well as a patient symptom visual analogue scale. The change in olfactory function and it's influence factors in NPC patients who receiving induction chemotherapy with concurrent chemoradiotherapy will be investigated.

Condition Nasopharyngeal Carcinoma
Clinical Study IdentifierNCT05146050
SponsorSun Yat-sen University
Last Modified on29 January 2023

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