Prospective Study About Sensitization Pattern to Insects as Food Source in Patients With House Dust Mite Allergy (InFood)

  • End date
    Dec 10, 2023
  • participants needed
  • sponsor
    University of Zurich
Updated on 10 March 2022
Accepts healthy volunteers


Patients allergic to seafood and/or sensitized to Tropomyosin of Skin Prick tests SPT or crustacean origin will may be also be sensitized to edible insects. Aim of the study is to evaluate whether patients allergic to seafood and/or sensitized to Tropomyosin of SPT or crustacean origin may be more often be sensitized to edible insects used as food source.


House dust mite allergy is a common problem in Europe. In addition to inhalant allergies sensitization to mites can be related to food allergy namely seafood. Insects are also widespread food sources in many regions of the world.

In this study skin testing and laboratory tests are planned in patients with known house dust mite allergy to evaluate a possible sensitization to insects. Patients must also complete a questionnaire. A drug therapy or other intervention is not planned.

Aim of the study is to evaluate whether patients allergic to seafood and/or sensitized to Tropomyosin of SPT or crustacean origin may be more often be sensitized to edible insects used as food source.

Condition Hypersensitivity, Food
Treatment Skin Prick Test
Clinical Study IdentifierNCT04239131
SponsorUniversity of Zurich
Last Modified on10 March 2022


Yes No Not Sure

Inclusion Criteria

Age: 18 < x < 70
House dust mite sensitization with or without sensitization to seafood
Subject is capable of giving informed consent
Signed informed consent

Exclusion Criteria

Use of antihistamines, systemic corticosteroids during testing and within three days (antihistamines) or two weeks (corticosteroids) prior to testing
Use of immunosuppressive agents
History of cancer except for treated basal cell or spinal cell carcinoma of the skin
Active or recurrent bacterial, fungal or viral infection at the time of enrollment, including patients with evidence of Human Immunodeficiency Virus (HIV) infection, Hepatitis B and Hepatitis C infection, active or untreated latent tuberculosis
Female patients of childbearing potential who are pregnant or breast feeding or planning a pregnancy during the duration of the trial and/or not practicing acceptable birth control for the duration of the trial
Known or suspected non-compliance, drug or alcohol abuse
Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc. of the participant
Previous enrollment into the current study
Enrollment of the investigator, his/her family members, employees and other dependent persons
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